A preliminary randomized, double blind cross-over clinical study on low dose garlic capsule was conducted to determine the efficacy, acceptability and adverse effects of the preparations. Garlic capsules (250 mg) and placebo capsules of the same size and weight were administered in 2 groups of patients (7 in group A and 6 in group B).
Results of administration of garlic capsules and placebo among all subjects showed that during the first 4 weeks of treatment, diastolic and systolic blood pressure were decreased to about the same degree whether garlic or placebo was given. However, from the 7th to the 10th week of therapy (after a 2 week washout) degree of blood pressure varied. A great fall in the blood pressure levels was observed among garlic-treated patients. Additionally, decrease in a heart rate was noted. (Author)
The project will assess the clinical efficacy and safety of garlic capsules, yerba buena tablets, sambong tablets, ampalaya capsule, ulasimang bato capsule, akapulko lotion and ipil-ipil suspension.